Intracellular integration of synthetic nanostructures with viable cells for controlled biochemical manipulation

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McKnight, T.E., A.V. Melechko, G.D. Griffin, M.A. Guillorn, V.I. Merkulov, F. Serna, D.K. Hensley, M.J. Doktycz, D.H. Lowndes, and M.L. Simpson, 
Nanotechnology, 2003. 14(5): p. 551-556


This image has been assembled in Adobe Photoshop by overlaying an optical microscope photograph and scanning electron micrograph that has been colorized and manipulated to display perspective.

Front: Scanning electron micrograph of chinese hamster ovary cells (CHO) following impalement on a nanofiber array. Background: Optical microscope image of a transformed colony of CHO expressing green fluorescent protein from nanofiber delivered plasmids 22 days following impalement upon DNA modified nanofiber array.
 

Expecting Big Things from Nanostructures

NANOSTRUCTURES OFFER NEW APPROACH TO CELL MANIPULATION

Cancer Nanotech (National Institute of Cancer) brochure
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PBS on Cancer Nanotech

National Institute of Biomedical Imaging and Bioengineering (found by Jason Heikenfeld)

Info in nanoshell

Nanopicture of the day

www.nano.gov report on Nanobiotechnology  (saved on this server)

The idea of impalefection is scribbled behind Tim McKnight's head on this photo