Intracellular integration of synthetic nanostructures with viable cells for controlled biochemical manipulation

McKnight, T.E., A.V. Melechko, G.D. Griffin, M.A. Guillorn, V.I. Merkulov, F. Serna, D.K. Hensley, M.J. Doktycz, D.H. Lowndes, and M.L. Simpson

Nanotechnology, 2003. 14(5): p. 551-556.

• Front: Scanning electron micrograph of chinese hamster ovary cells (CHO) following impalement on a nanofiber array.
• Background: Optical microscope image of a transformed colony of CHO expressing green fluorescent protein from nanofiber delivered plasmids 22 days following impalement upon DNA modified nanofiber array.
• This image has been assembled in Adobe Photoshop by overlaying an optical microscope photograph and scanning electron micrograph, which has been colorized and manipulated to display fake perspective.  

 

The idea of impalefection is scribbled behind Tim McKnight's head on this photo

 

• Expecting Big Things from Nanostructures
•  NANOSTRUCTURES OFFER NEW APPROACH TO CELL MANIPULATION
• Cancer Nanotech (National Institute of Cancer) brochure [local save]
• PBS on Cancer Nanotech
•  National Institute of Biomedical Imaging and Bioengineering (found by Jason Heikenfeld)
• Info in nanoshell
•  Nanopicture of the day
•  www.nano.gov report on Nanobiotechnology  (saved on this server)